User:Douglas Robert Kelly

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In 1999 I commenced a BSc at the University of Adelaide studying Chemistry, Biochemistry, Microbiology & Immunology with strong interests in Pharmacology/Toxicology and Physiology earning me a position in the Golden Key International Honour Society. After being awarded top hons prize in 2002 for my research on calcium waves in isolated cardiomyocytes I commenced a PhD with Assoc Prof David Saint investigating the effects of stretch on cardiac electrophysiology in the mammalian heart. Nearing completion of my PhD on cardiac electrophysiology in 2007, I joined the Cardiovascular Researh Center (CRC, Royal Adelaide Hospital) in a postdoctoral/research fellow position. Current laboratory research involves the use of various electrophysiological techniques ranging from basic monophasic surface recordings to complex cellular techniques including transcellular recordings and patch clamping. Here, we also investigate complex electrophysiological responses using multiple electrode arrays (MEAs) to record changes in conduction heterogeneity, velocity and refractory periods. Using these various methods we can study the changes in cardiac electrophysiology throughout the progression of various disease states including myocardial infarction, hypertension and atrial fibrillation.